STANDARD V14.4 • ROUTAGE O(1) 24-pole relational architecture & 17 Index-Experts™ synchronized with NCBI 2026 taxonomy, EBI SIFTS 3D and cFMD/FMBN.
🎛️ Profile Selection & Cognitive Granularity (0 ms) 🧬 Palier 5 — Expert Absolu
1 5
🔎 Click any sourced badge to verify its proof
🎛️ Cognitive Granularity Slider (Progressive Disclosure 1 → 5)
Click any tier (1 to 5) to instantaneously filter the displayed scientific depth:
Palier 1 • Identité NCBI 🦠 NCBI TAXID #29459 • SPECIES • Bacteria 🔎 NCBI Certificate #29459
← Back to portal

Brucella melitensis Brucella melitensis (Hughes 1893) Meyer and Shaw 1920 (Approved Lists 1980) emend. Verger et al. 1985

🌍 Brucellosis pathogen (Malta fever agent) ; Agent pathogène de la brucellose (fièvre de Malte)

⚡ 3 active Index-Experts™ pole(s) (O(1) routing)  •  🧀 0 linked cheese matrix/matrices  •  🧊 25 3D structure(s) RCSB PDB / EBI SIFTS

🌳 Phylogenetic Lineage & Associated Cheese Matrices

Palier 2 • Fromager & Sommelier
Pseudomonadota (phylum) › Alphaproteobacteria (class) › Hyphomicrobiales (order) › Brucellaceae (family) › Brucella (genus)

🧫 Isolation Substrates, Biological Hosts & Cellar Ecology (NCBI Host)

Palier 3 • Praticien & Affineur
Fromages frais et pâtes molles au lait cru de brebis et de chèvre
INDEX-EXPERT™ #01 • Tyrodexia™ Architecture Palier 5

Synonyms and historical names (NCBI)

🔎 SQLite Proof
Nomenclature concordance (NCBI) Brucella melitensis ⟷ Brucella melitensis (Hughes 1893) Meyer and Shaw 1920 (Approved Lists 1980) • Micrococcus melitensis
Historical synonyms & basionyms Brucellosis pathogen (Malta fever agent) ; Agent pathogène de la brucellose (fièvre de Malte) • Bacteria
Taxonomic authority & reference strains Brucella melitensis (Hughes 1893) Meyer and Shaw 1920 (Approved Lists 1980) emend. Verger et al. 1985
Official sources & reference book TaxID:29459 • Le grand dictionnaire du microbiome des fromages (https://www.tyrodexia.com/index.html#ouvrage)
Lineage & phylogenomic justification Pseudomonadota (phylum) › Alphaproteobacteria (class) › Hyphomicrobiales (order) › Brucellaceae (family) › Brucella (genus)
PubMed taxonomic references PMID:24657159 🔎 • DOI:10.1016/j.ijfoodmicro.2014.02.016 🔎
INDEX-EXPERT™ #06 • Tyrodexia™ Architecture Palier 3

Symptoms and manufacturing defects

🔎 SQLite Proof
Vigilance category & defect diagnosis Agent pathogène de la brucellose (fièvre de Malte) • Absence totale de signe visuel ou olfactif sur le fromage ; zoonose majeure réglementée provoquant une fièvre ondulante septicémique
Spoilage metabolites & taxonomic lineage Excrétion directe dans le lait par la glande mammaire infectée et résistance à la phagocytose ainsi qu'à l'acidification modérée des pâtes fraîches
Documented substrates & historical synonyms Statut officiellement indemne des cheptels ovins/caprins, pasteurisation du lait ou affinage prolongé (> 60 jours avec acidification lactique stricte) • Lait cru issu de troupeaux non indemnes, pH > 5.0, affinage court (< 60 jours), survie intracellulaire dans les leucocytes du lait
Official sources & reference book TaxID:29459 • Le manuel clinique des pathologies laitières et fromagères (https://www.tyrodexia.com/index.html#collection)
Reference strain collections ATCC 23456, NCTC 10094, CIP 104252 (Souche 16M)
Operator safety & PubMed references PMID:24657159 🔎 • DOI:10.1016/j.ijfoodmicro.2014.02.016 🔎
INDEX-EXPERT™ #08 • Tyrodexia™ Architecture Palier 4

Pathogens and bioprotection

🔎 SQLite Proof
Bacteriocins (NPClassifier) & health targets Brucellosis pathogen (Malta fever agent) ; Agent pathogène de la brucellose (fièvre de Malte) • Bacteria
Isolation substrates & linked cheese matrices Fromages frais et pâtes molles au lait cru de brebis et de chèvre • Pseudomonadota (phylum) › Alphaproteobacteria (class) › Hyphomicrobiales (order) › Brucellaceae (family) › Brucella (genus)
Physicochemical barriers (TDM, moisture, NaCl USDA) Brucella melitensis (Hughes 1893) Meyer and Shaw 1920 (Approved Lists 1980) emend. Verger et al. 1985 • Brucella melitensis (Hughes 1893) Meyer and Shaw 1920 (Approved Lists 1980) • Micrococcus melitensis
Official sources & reference book TaxID:29459 • Le manuel clinique des pathologies laitières et fromagères (https://www.tyrodexia.com/index.html#collection)
Prophylaxis & PubMed references PMID:24657159 🔎 • DOI:10.1016/j.ijfoodmicro.2014.02.016 🔎

⚠️ Cellar Clinical Vigilance & Generic Defects Monitoring (1)

Differential diagnosis of potential defects, biochemical mechanisms and cellar prophylaxis (Tier 3 — Practitioner):

⚠️ Brucellosis pathogen (Malta fever agent)
PATHOGENE_REGLEMENTAIRE_STRICT🔎 Proof
Absence totale de signe visuel ou olfactif sur le fromage ; zoonose majeure réglementée provoquant une fièvre ondulante septicémique
View full 360° clinical card →

🏛️ Global Culture Collections (DSM / ATCC / CBS), NCBI Synonyms, Strains & FAO DAD-IS Breeds

Palier 4 • Institutionnel & Microbiologiste
NCBI Synonyms & Basionyms Brucella melitensis (Hughes 1893) Meyer and Shaw 1920 (Approved Lists 1980) • Micrococcus melitensis
🔬 Subordinate strains and subspecies qualified in Tyrodexia™ (48) :
🦠 Brucella melitensis 02-5863-1 #1341686 🦠 Brucella melitensis 02-7258 #1388745 🦠 Brucella melitensis 043 #1266367 🦠 Brucella melitensis 11-1823-3434 #1388740 🦠 Brucella melitensis 16M13W #1143191 🦠 Brucella melitensis 16M1W #1143190 🦠 Brucella melitensis 548 #1457189 🦠 Brucella melitensis 64/150 #1160220 🦠 Brucella melitensis 66/59 #1160224 🦠 Brucella melitensis ADMAS-G1 #1351836 🦠 Brucella melitensis ATCC 23457 #546272 🦠 Brucella melitensis B115 #1247411 🦠 Brucella melitensis BG2 (S27) #1169223 🦠 Brucella melitensis CNGB 1076 #1198679 🦠 Brucella melitensis CNGB 1120 #1198680 🦠 Brucella melitensis CNGB 290 #1198681 🦠 Brucella melitensis F1/06 B10 #1160219 🦠 Brucella melitensis F10/05-2 #1160211 🦠 Brucella melitensis F10/06-16 #1169224 🦠 Brucella melitensis F15/06-7 #1244532 🦠 Brucella melitensis F2/06-6 #1160226 🦠 Brucella melitensis F3/02 #1160210 🦠 Brucella melitensis F5/07-239A #1160215 🦠 Brucella melitensis F6/05-6 #1169225 🦠 Brucella melitensis F8/01-155 #1160225 🦠 Brucella melitensis F9/05 #1169226 🦠 Brucella melitensis M28 #941967 🦠 Brucella melitensis M5 #1286630 🦠 Brucella melitensis M5-10 #1210452 🦠 Brucella melitensis M5-90 #703352 🦠 Brucella melitensis NI #1029825 🦠 Brucella melitensis R3/07-2 #1160218 🦠 Brucella melitensis S66 #1148757 🦠 Brucella melitensis UK14/06 #1160217 🦠 Brucella melitensis UK19/04 #1160223 🦠 Brucella melitensis UK22/04 #1160214 🦠 Brucella melitensis UK22/06 #1160221 🦠 Brucella melitensis UK23/06 #1160213 🦠 Brucella melitensis UK29/05 #1169227 🦠 Brucella melitensis UK3/06 #1169228 🦠 Brucella melitensis UK31/99 #1169229 🦠 Brucella melitensis UK37/05 #1160216 🦠 Brucella melitensis Uk24/06 #1160222 🦠 Brucella melitensis bv. 1 #644337 🦠 Brucella melitensis bv. 1 str. 133 #1229906 🦠 Brucella melitensis bv. 1 str. 16M #224914 🦠 Brucella melitensis bv. 1 str. BCB028 #1210447 🦠 Brucella melitensis bv. 1 str. BCB033 #1210449

🧬 RefSeq Genomics, 3D Structural Biology (EBI SIFTS), Metagenomics (cFMD/FMBN) & PubMed

Palier 5 • Expert Absolu
EBI SIFTS / RCSB PDB 3D Structures PDB #10UH (25 crystallographic structures • CIF) — RCSB PDB 3D ↗
NCBI RefSeq Genomic Assembly RefSeq: GCA_000007125.1 • Taille: 3.29493 Mb • GC: 57.2357 % • Statut: Complete Genome • BioSample: SAMN40893484 • BioProject: PRJNA1097985
PubMed / DOI Primary Literature PMID:24657159 🔎 • DOI:10.1016/j.ijfoodmicro.2014.02.016 🔎