STANDARD V14.4 • ROUTAGE O(1) 24-pole relational architecture & 17 Index-Experts™ synchronized with NCBI 2026 taxonomy, EBI SIFTS 3D and cFMD/FMBN.
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Palier 1 • Identité NCBI 🦠 NCBI TAXID #28038 • SPECIES • Bacteria 🔎 NCBI Certificate #28038
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Latilactobacillus curvatus "Bacterium curvatum" Troili-Petersson 1903

🌍 NSLAB late slit defect and tyramine/putrescine accumulation agent ; Agent lactique non-starter (NSLAB) de fentes tardives et d'accumulation de tyramine/putrescine

⚡ 3 active Index-Experts™ pole(s) (O(1) routing)  •  🧀 17 linked cheese matrix/matrices  •  🧊 1 3D structure(s) RCSB PDB / EBI SIFTS

🌳 Phylogenetic Lineage & Associated Cheese Matrices

Palier 2 • Fromager & Sommelier
Bacillota (phylum) › Bacilli (class) › Lactobacillales (order) › Lactobacillaceae (family) › Latilactobacillus (genus)
🧀 Linked cheeses, dairy matrices and designations (17) :
🧀 Blue cheese 🧀 Caciocavallo 🧀 Cheddar cheese 🧀 Cheese core 🧀 Edam 🧀 Feta 🧀 Fontina 🧀 Gamoneu 🧀 Idiazabal 🧀 Monte veronese 🧀 Pecorino 🧀 Pecorino toscano 🧀 Picon bejes tresviso 🧀 Provolone 🧀 Queso palmero 🧀 Taleggio 🧀 Tomme cheese from cow's milk

🧫 Isolation Substrates, Biological Hosts & Cellar Ecology (NCBI Host)

Palier 3 • Praticien & Affineur
Cheddar, Gouda, Edam, pâtes pressées non cuites et demi-cuites affinées sous film
INDEX-EXPERT™ #01 • Tyrodexia™ Architecture Palier 5

Synonyms and historical names (NCBI)

🔎 SQLite Proof
Nomenclature concordance (NCBI) Latilactobacillus curvatus ⟷ Bacterium curvatum • Lactobacillus curvatus
Historical synonyms & basionyms NSLAB late slit defect and tyramine/putrescine accumulation agent ; Agent lactique non-starter (NSLAB) de fentes tardives et d'accumulation de tyramine/putrescine • Bacteria
Taxonomic authority & reference strains "Bacterium curvatum" Troili-Petersson 1903
Official sources & reference book TaxID:28038 • Le grand dictionnaire du microbiome des fromages (https://www.tyrodexia.com/index.html#ouvrage)
Lineage & phylogenomic justification Bacillota (phylum) › Bacilli (class) › Lactobacillales (order) › Lactobacillaceae (family) › Latilactobacillus (genus)
PubMed taxonomic references PMID:32293557 🔎 • DOI:10.1099/ijsem.0.004107 🔎
INDEX-EXPERT™ #06 • Tyrodexia™ Architecture Palier 3

Symptoms and manufacturing defects

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Vigilance category & defect diagnosis Agent lactique non-starter (NSLAB) de fentes tardives et d'accumulation de tyramine/putrescine • Fentes internes horizontales (slits), gonflement lâche des sachets sous-vide, goût acide-amer et accumulation de tyramine et putrescine • Provolone [en:provolone], Taleggio [en:taleggio], Pecorino toscano [it:pecorino-toscano], Fontina [en:fontina], Monte veronese [it:monte-veronese], Pecorino [en:pecorino]
Spoilage metabolites & taxonomic lineage Métabolisme hétérofermentaire facultatif et co-métabolisme du citrate/acides aminés libérant du CO2, couplé aux voies tyrosine décarboxylase (Tdc) et agmatine désiminase (AgDI)
Documented substrates & historical synonyms Sélection de levains primaires épuisant totalement les sucres, maîtrise de la température de cave (< 8 °C) et contrôle de la flore NSLAB d'atelier • Psychrotolérance (croissance dès 4-6 °C), halotolérance (> 6 % NaCl), présence de citrate ou de sucres résiduels, survie à la pasteurisation
Official sources & reference book TaxID:28038 • Le manuel clinique des pathologies laitières et fromagères (https://www.tyrodexia.com/index.html#collection)
Reference strain collections DSM 20019, ATCC 25601, NCTC 13769, CIP 102992
Operator safety & PubMed references PMID:32293557 🔎 • DOI:10.1099/ijsem.0.004107 🔎
INDEX-EXPERT™ #08 • Tyrodexia™ Architecture Palier 4

Pathogens and bioprotection

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Bacteriocins (NPClassifier) & health targets Flore de vigilance métagénomique (2 éch.) ; Flore de vigilance métagénomique (4 éch.) ; Flore de vigilance métagénomique (24 éch.) • NSLAB late slit defect and tyramine/putrescine accumulation agent ; Agent lactique non-starter (NSLAB) de fentes tardives et d'accumulation de tyramine/putrescine • Bacteria
Isolation substrates & linked cheese matrices Cheddar, Gouda, Edam, pâtes pressées non cuites et demi-cuites affinées sous film • Feta [en:feta], Fontina [en:fontina], Gamoneu [es:gamoneu], Taleggio [en:taleggio], Idiazabal [es:idiazabal], Queso palmero [es:queso-palmero], Monte veronese [it:monte-veronese], Pecorino toscano [it:pecorino-toscano] • Bacillota (phylum) › Bacilli (class) › Lactobacillales (order) › Lactobacillaceae (family) › Latilactobacillus (genus)
Physicochemical barriers (TDM, moisture, NaCl USDA) Feta (EST 44.8 %, MNA 70.32 %, NaCl 2.9 g/100g) ; Fontina (EST 62.1 %, MNA 55.01 %, NaCl 2.03 g/100g) ; Gamoneu (EST 10.9 %, MNA 89.34 %, NaCl 1.2 g/100g) ; Taleggio (EST 33.2 %, MNA 71.06 %, NaCl 0.94 g/100g) • "Bacterium curvatum" Troili-Petersson 1903 • Bacterium curvatum • Lactobacillus curvatus
Official sources & reference book TaxID:28038 • Le manuel clinique des pathologies laitières et fromagères (https://www.tyrodexia.com/index.html#collection)
Prophylaxis & PubMed references PMID:32293557 🔎 • DOI:10.1099/ijsem.0.004107 🔎

⚠️ Cellar Clinical Vigilance & Generic Defects Monitoring (2)

Differential diagnosis of potential defects, biochemical mechanisms and cellar prophylaxis (Tier 3 — Practitioner):

⚠️ Putrescine accumulation agent
DEFAUT_PATE_GAZ_FENTES🔎 Proof
Fentes internes horizontales (slits), gonflement lâche des sachets sous-vide, goût acide-amer et accumulation de tyramine et putrescine • Pâte spon…
View full 360° clinical card →
⚠️ NSLAB late slit defect and tyramine
DEFAUT_PATE_GAZ_FENTES🔎 Proof
Fentes internes horizontales (slits), gonflement lâche des sachets sous-vide, goût acide-amer et accumulation de tyramine et putrescine
View full 360° clinical card →

🏛️ Global Culture Collections (DSM / ATCC / CBS), NCBI Synonyms, Strains & FAO DAD-IS Breeds

Palier 4 • Institutionnel & Microbiologiste
NCBI Synonyms & Basionyms Bacterium curvatum • Lactobacillus curvatus
🔬 Subordinate strains and subspecies qualified in Tyrodexia™ (2) :
🦠 Latilactobacillus curvatus CRL 705 #1074451 🦠 Latilactobacillus curvatus JCM 1096 = DSM 20019 #1293592

🧬 RefSeq Genomics, 3D Structural Biology (EBI SIFTS), Metagenomics (cFMD/FMBN) & PubMed

Palier 5 • Expert Absolu
EBI SIFTS / RCSB PDB 3D Structures PDB #2A2B (1 crystallographic structures • CIF) — RCSB PDB 3D ↗
NCBI RefSeq Genomic Assembly RefSeq: GCA_004101845.1 • Taille: 1.91652 Mb • GC: 41.9856 % • Statut: Complete Genome • BioSample: SAMN38021392 • BioProject: PRJNA964705
PubMed / DOI Primary Literature PMID:32293557 🔎 • DOI:10.1099/ijsem.0.004107 🔎
📊 Quantitative Metagenomic Detections (SegataLab/cFMD Cell 2024 & FoodMicrobionet) :
📊 SegataLab/cFMD (Cell 2024) : en:cheeses (n=94) 📊 SegataLab/cFMD (Cell 2024) : en:cheddar-cheese (n=24) 📊 SegataLab/cFMD (Cell 2024) : en:caciocavallo (n=14) 📊 SegataLab/cFMD (Cell 2024) : en:cheese-core (n=6) 📊 SegataLab/cFMD (Cell 2024) : en:taleggio (n=4) 📊 SegataLab/cFMD (Cell 2024) : en:provolone (n=2) 📊 SegataLab/cFMD (Cell 2024) : it:pecorino-toscano (n=2) 📊 SegataLab/cFMD (Cell 2024) : en:fontina (n=2) 📊 SegataLab/cFMD (Cell 2024) : it:monte-veronese (n=2) 📊 SegataLab/cFMD (Cell 2024) : en:pecorino (n=2) 📊 SegataLab/cFMD (Cell 2024) : en:feta (n=2) 📊 SegataLab/cFMD (Cell 2024) : en:tomme-cheese-from-cow-s-milk (n=2) 📊 SegataLab/cFMD (Cell 2024) : es:picon-bejes-tresviso (n=2) 📊 SegataLab/cFMD (Cell 2024) : es:gamoneu (n=2) 📊 SegataLab/cFMD (Cell 2024) : es:queso-palmero (n=2) 📊 SegataLab/cFMD (Cell 2024) : es:idiazabal (n=2) 📊 SegataLab/cFMD (Cell 2024) : en:blue-cheese (n=2) 📊 SegataLab/cFMD (Cell 2024) : en:edam (n=2)