⚡ Index-Expert™ #06 — Symptoms, Manufacturing Defects and Vigilance • PATHOGENE_REGLEMENTAIRE_STRICT

Paratuberculosis (Johne's disease) thermotolerant persistence agent in cheese

Aucune altération visuelle, texturale ou olfactive du fromage ; danger sanitaire surveillé (entérite granulomateuse des ruminants et lien épidémiologique étudié avec la maladie de Crohn)

🧀 0 concerned cheese(s) & family(ies)  •  🦠 1 linked living taxon(s)

🔍 Clinical, Sensory & Functional Diagnosis

Aucune altération visuelle, texturale ou olfactive du fromage ; danger sanitaire surveillé (entérite granulomateuse des ruminants et lien épidémiologique étudié avec la maladie de Crohn)

🧬 Biochemical, Enzymatic & Genetic Mechanism

Paroi cellulaire riche en lipides complexes et acides mycoliques (mycobactine-dépendante pour la subsp. paratuberculosis) empêchant la lyse acide et saline pendant plusieurs mois d'affinage

🌡️ Physicochemical Parameters & Target Matrices

Excrétion mammaire et fécale dans le lait cru et survie prolongée durant la fabrication et l'affinage • Troupeaux infectés par la paratuberculose, haute résistance thermique (survie partielle à la thermisation et à la pasteurisation basse en amas cellulaires) et tolérance à pH 4.5-5.0

🛡️ Cellar Protocol, Prophylaxis & Biocontrol

Certification et assainissement des cheptels vis-à-vis de la paratuberculose, hygiène stricte de la traite, microfiltration du lait et affinage prolongé

📚 Specialized Sources & Publications (HAL-INRAE, UniProtKB, DOI, PubMed)

PMID:15653520 ↗ • DOI:10.1128/AEM.71.3.1239-1247.2005 ↗ • Clara Marcé et al. (2009) — Higher non-return rate associated with Mycobacterium avium subspecies paratuberculosis infection at early stage in Holstein dairy cows [Theriogenology] • DOI:10.1016/j.theriogenology.2008.10.017 ↗ • Floor Biemans et al. (2022) — Modelling transmission of Mycobacterium avium subspecies paratuberculosis between Irish dairy cattle herds [Veterinary Research] • DOI:10.1186/s13567-022-01066-5 ↗

🦠 Living Taxa Linked to This Concept / Symptom (1)

🔮 Other Cards in Index-Expert™ #06 — Symptoms, Manufacturing Defects and Vigilance (334)

Halotolerant cheese-brine and slimy ammoniacal smear defect agent (5🧀 / 1🦠) Red cellar spot (orange-red rind pocking) fungal agent (5🧀 / 1🦠) Extreme halophilic brine turbidity, slimy smear and putrid off-odor agent (4🧀 / 1🦠) Arthroconidial yeast-like greasy smear, wrinkled rind and ammoniacal off-odor agent (4🧀 / 1🦠) Rind swarming, ammoniacal (4🧀 / 1🦠) Putrid, fecal and barnyard rind off-odor agent (4🧀 / 1🦠) Late butyric blowing defect agent (4🧀 / 1🦠) Halotolerant dark-brown powdery rind scab and ammoniacal off-odor fungal agent (4🧀 / 1🦠) Extreme xerophilic grey-green and yellow-cleistothecial rind mold on aged hard cheeses (4🧀 / 1🦠) Heterofermentative NSLAB secondary gas-blowing, histamine and pinking defect agent (3🧀 / 2🦠) Halophilic basidiomycetous yeast brine contaminant and chalky-yellow smear defect agent (4🧀 / 1🦠) Halophilic cheese-brine pellicle, turbidity and brine deacidification yeast agent (4🧀 / 1🦠) NSLAB post-acidification, calcium lactate crystal efflorescence and tyramine agent (3🧀 / 2🦠) Salmonellosis foodborne pathogen (4🧀 / 1🦠) Propionic orange-red spot and late split defect agent (4🧀 / 1🦠) Halotolerant psychrotrophic floral (4🧀 / 1🦠) Major co-agent of late butyric blowing defect (4🧀 / 1🦠) Musty off-odor and slimy rind agent (4🧀 / 1🦠) Putrescine accumulation agent (3🧀 / 2🦠) Putrid off-odor and putrescine accumulation agent (4🧀 / 1🦠) Halophilic brine slime, sticky smear and sulfurous-putrid off-odor agent (3🧀 / 1🦠) Putrid, ammoniacal (3🧀 / 1🦠) Putrid-fecal smear off-odor and reddish-brown sub-rind discoloration agent (3🧀 / 1🦠) Brine flower (mycodermic film) and solvent off-flavor yeast agent (3🧀 / 1🦠) Blue-green mold spot and musty (3🧀 / 1🦠)